Which means Genesis is dead. What else could a lack of success mean? It would probably bother him one day, but now .. now it's just a name and a potential event. Something to put a pin in for later, so when he finally actually encountered this person perhaps a start to finding a cure could happen sooner.

Or end his suffering sooner.

"Thank you for your honesty." Sephiroth's one friend in the future, and he dies thanks to unethical experiments that went wrong. That tracked. "It sounds as if you were assigned dealing with the matter yourself. It shouldn't have fallen to you. I'll do better." He had to. That was a personal failing, he suspected, that fatal flaw he'd been warned of about friendships that led to emotions and bad decisions. The leaders always had the responsibility of seeing to their subordinates one way or another, and Sephiroth doubted Shinra would allow anyone to outrank their poster boy.

Then again. Maybe he'd been replaced by then. Prototypes were always destined to get a perfected version. Was that too much to hope for?